HKL Research, Inc. licenses and supports the HKL-2000 and the HKL-3000 software widely used in structural biology.

The flagship software, HKL-2000, has been used by over 100 pharmaceutical companies and over 1200 academic, governmental, and non-profit institutions. The software is also available at many synchrotron beam lines. The paper describing this software has over 30,000 citations in leading scientific journals and is 23^rd among the top 100 most frequently cited scientific papers of all time. It has been reported to be used in the structure determination process in over 50% of all X-ray crystallography structures deposited to the Protein Data Bank (PDB). 

The HKL-3000 software combines all functions of the HKL-2000 program with a number of other macromolecular crystallographic computer programs: CCP4 suite, the ARP/wARP suite, the SHELX-97 suite, the SOLVE/RESOLVE suite, Coot, PyMOL and Buccaneer. Over 550 published papers reported the use of HKL-3000.

HKL Research, Inc. provides the following services for X-ray crystallography laboratories:

• Distribution and support of the HKL-2000 package
• Distribution and support of the HKL-3000 package
• Data processing service

Information in this document is subject to change without notice. Denzo®, HKL®, and HKL-2000® are registered trademarks of HKL Research, Inc. Other products and companies referred to herein are trademarks or registered trademarks of their respective companies or mark holders.